Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | CCR5 | P51681 | 6/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271445 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL19112523 | 0.80 | SLC6A4 (0.52) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL19112598 | 0.79 | SLC6A4 (0.51) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL4284264 | 0.78 | SLC6A4 (0.48) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL4272761 | 0.77 | SLC6A4 (0.49) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL19113877 | 0.77 | SLC6A4 (0.47) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL4280885 | 0.77 | SLC6A4 (0.48) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL19113057 | 0.77 | SLC6A4 (0.48) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL4273319 | 0.77 | SLC6A4 (0.48) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 | |
| SCHEMBL4280527 | 0.76 | SLC6A4 (0.48) | SLC6A4SLC6A3CCR5SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Taro Pharmaceuticals Inc. (CA) | 2017-07-12 | — | — | EP | disclosed |