Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 10/20 | 0.52 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277752 | 0.94 | KCNH2 (0.58) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4276878 | 0.94 | KCNH2 (0.58) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL20056383 | 0.91 | KCNH2 (0.54) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4276594 | 0.90 | KCNH2 (0.52) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL20056337 | 0.85 | KCNH2 (0.57) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL19113391 | 0.83 | KCNH2 (0.57) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4269237 | 0.83 | KCNH2 (0.64) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4279329 | 0.82 | KCNH2 (0.62) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4274259 | 0.82 | KCNH2 (0.62) | KCNH2CACNA1IRORCCACNA1GCACNA1H | |
| SCHEMBL4274233 | 0.82 | KCNH2 (0.62) | KCNH2CACNA1IRORCCACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Taro Pharmaceuticals Inc. (CA) | 2017-07-12 | — | — | EP | disclosed |