Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 12/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271076 | 0.93 | KCNH2 (0.55) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4270195 | 0.87 | KCNH2 (0.61) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4285626 | 0.87 | KCNH2 (0.61) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4274763 | 0.82 | KCNH2 (0.57) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL19113176 | 0.82 | KCNH2 (0.58) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4277349 | 0.82 | KCNH2 (0.56) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4275313 | 0.82 | KCNH2 (0.56) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL4276605 | 0.81 | KCNH2 (0.58) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL13569757 | 0.81 | KCNH2 (0.55) | CACNA1ICACNA1GCACNA1HKCNH2 | |
| SCHEMBL19113096 | 0.80 | KCNH2 (0.60) | CACNA1ICACNA1GCACNA1HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Taro Pharmaceuticals Inc. (CA) | 2017-07-12 | — | — | EP | disclosed |