Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 6/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050578 | 0.92 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7691493 | 0.88 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7752465 | 0.85 | CPN1 (0.44) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16244189 | 0.81 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL19812708 | 0.80 | AOC3 (0.37) | SLC1A3SLC1A2SLC1A1PDE4D | |
| SCHEMBL18787635 | 0.80 | AOC3 (0.37) | SLC1A3SLC1A2SLC1A1PDE4D | |
| SCHEMBL18787634 | 0.80 | AOC3 (0.37) | SLC1A3SLC1A2SLC1A1PDE4D | |
| SCHEMBL18787795 | 0.80 | AOC3 (0.37) | SLC1A3SLC1A2SLC1A1PDE4D | |
| SCHEMBL16877155 | 0.75 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1LMNAMAPT | |
| SCHEMBL20569467 | 0.75 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | disclosed |