Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900662 | 0.97 | — | — | |
| SCHEMBL18271379 | 0.97 | — | — | |
| SCHEMBL12938791 | 0.78 | SMN1; SMN2 (0.39) | GBA1SMN1; SMN2 | |
| SCHEMBL18542747 | 0.78 | SMN1; SMN2 (0.39) | GBA1SMN1; SMN2 | |
| SCHEMBL14367703 | 0.78 | — | — | |
| SCHEMBL24235270 | 0.78 | — | — | |
| SCHEMBL11992654 | 0.78 | GBA1 (0.31) | GBA1 | |
| SCHEMBL24970735 | 0.78 | GBA1 (0.31) | GBA1 | |
| SCHEMBL26121598 | 0.78 | — | — | |
| SCHEMBL835259 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9847555-B2 | Power storage device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170207487-A1 | POWER STORAGE DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2017-07-20 | — | — | US | disclosed |