Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431818 | 0.92 | F10 (0.87) | F10KCNH2KLKB1 | |
| SCHEMBL2431134 | 0.90 | F10 (1.00) | F10KCNH2KLKB1F2 | |
| SCHEMBL19128999 | 0.89 | F10 (0.72) | F10KCNH2KLKB1 | |
| SCHEMBL10146279 | 0.88 | F10 (1.00) | F10KCNH2F2 | |
| SCHEMBL2438967 | 0.87 | F10 (0.79) | F10KCNH2KLKB1F2 | |
| SCHEMBL6107538 | 0.87 | F10 (0.70) | F10KCNH2KLKB1 | |
| SCHEMBL2439114 | 0.87 | F10 (0.78) | F10KCNH2 | |
| SCHEMBL5392608 | 0.86 | F10 (0.79) | F10KCNH2KLKB1 | |
| SCHEMBL6109322 | 0.85 | F10 (0.67) | F10KCNH2KLKB1 | |
| SCHEMBL10146317 | 0.85 | F10 (0.77) | F10KCNH2KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708265-B2 | Urethanes, ureas, amidines and related inhibitors of factor Xa | PHARMADIALL LIMITED LIABILITY COMPANY (RU) | 2017-07-18 | — | — | US | disclosed |
| US-9708265-B2 | Urethanes, ureas, amidines and related inhibitors of factor Xa | PHARMADIALL LIMITED LIABILITY COMPANY (RU) | 2017-07-18 | — | — | US | disclosed |