SCHEMBL1912949

SCHEMBL1912949

O=C(OC1CCNCC1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 0.61
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
GAA P10253 1/20 0.55
CHRM3 P20309 2/20 0.55
HTR3E A5X5Y0 1/20 0.54
HTR3B O95264 1/20 0.54
HTR3A P46098 1/20 0.54
HTR3D Q70Z44 1/20 0.54
HTR3C Q8WXA8 1/20 0.54
APOBEC3A P31941 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
HRH1 P35367 2/20 0.51
SCN1A P35498 1/20 0.51
SCN2A Q99250 1/20 0.51
SCN3A Q9NY46 1/20 0.51
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9312509 0.98 MEN1 (0.62) CHRNA7MEN1KMT2AGAACHRM3
Methylene Chloride SCHEMBL29003840 0.94 CHRNA7 (0.55) CHRNA7MEN1KMT2AGAACHRM3
SCHEMBL29068614 0.91 CHRNA7 (0.52) CHRNA7MEN1KMT2AGAACHRM3
SCHEMBL14390376 0.90 CHRNA7 (0.58) CHRNA7MEN1KMT2AGAACHRM3
SCHEMBL760593 0.90 CHRNA7 (0.58) CHRNA7MEN1KMT2AGAACHRM3
SCHEMBL760594 0.90 CHRNA7 (0.58) CHRNA7MEN1KMT2AGAACHRM3
Hydrochloric Acid SCHEMBL1723210 0.88 CHRNA7 (0.56) CHRNA7MEN1KMT2AGAACHRM3
Hydrochloric Acid SCHEMBL1723211 0.88 CHRNA7 (0.56) CHRNA7MEN1KMT2AGAACHRM3
SCHEMBL1786140 0.87 MEN1 (0.69) CHRNA7MEN1KMT2AGAAHTR3E
SCHEMBL4453290 0.87 MEN1 (0.69) CHRNA7MEN1KMT2AGAAHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US disclosed
WO-2024125346-A1 PREPARATION OF DEUTERATED 4-PHENYLPIPERIDINE-4-OL COMPOUND AND USE THEREOF 南昌双天使生物科技开发有限公司 2024-06-20 WO disclosed
CN-117447388-B Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound 南昌双天使生物科技开发有限公司 2024-05-10 CN disclosed
CN-117447385-B Preparation and application of deuterated 3-aminomethyl-4-phenylpiperidin-4-ol compound 南昌双天使生物科技开发有限公司 2024-05-10 CN disclosed
CN-117447385-A Preparation and application of deuterated 3-aminomethyl-4-phenylpiperidin-4-ol compound 南昌双天使生物科技开发有限公司 2024-01-26 CN disclosed
CN-117447388-A Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound 南昌双天使生物科技开发有限公司 2024-01-26 CN disclosed
EP-3567041-B1 SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF IMPACT THERAPEUTICS SHANGHAI INC (CN) 2023-12-27 EP disclosed
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-07-13 US disclosed
CN-108456204-B Benzothiazine derivative, and preparation method and application thereof 四川大学 2023-05-26 CN disclosed
EP-3567041-A9 SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF Impact Therapeutics (Shanghai), Inc (CN) 2022-04-20 EP disclosed
US-5661148-A ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER TEIJIN LIMITED (JP) 1997-08-26 US disclosed
EP-0514540-B1 PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LTD (JP) 1996-07-17 EP disclosed
CN-1075960-A Amino benzoyl guanidine, its preparation method that replaces is as the purposes and the medicament that contains it of medicine HOECHST AG (DE) 1993-09-08 CN disclosed
EP-0514540-A1 PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1992-11-25 EP disclosed
EP-0157472-B1 PROCESS FOR POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-03-07 EP disclosed
EP-0155847-B1 A STABILIZER FOR SYNTHETIC RESINS AND RESINS STABILIZED THEREBY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-08 EP disclosed
EP-0171139-B1 HIGH POLYMER STABILIZER CONTAINING A PHENOLIC COMPOUND, AND HIGH POLYMERS STABILIZED THEREBY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-26 EP disclosed
EP-0156512-B1 PROCESS FOR PREPARING CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-06-14 EP disclosed
EP-0106618-B1 STABILIZERS FOR SYNTHETIC RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-02-10 EP disclosed
EP-0102193-B1 STABILIZERS FOR SYNTHETIC RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 CHRNA7 243/4885MEN1 3316/4885KMT2A 4062/4885
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE ALK, ACVR1, ACVR2A CHRNA7 560/4885MEN1 3345/4885KMT2A 3260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.