Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381014 | 0.93 | GPBAR1 (0.51) | GPBAR1PRKCD | |
| SCHEMBL17380790 | 0.90 | GPBAR1 (0.49) | GPBAR1PRKCD | |
| SCHEMBL19129812 | 0.90 | GPBAR1 (0.49) | GPBAR1PRKCD | |
| SCHEMBL19129795 | 0.87 | TDP1 (0.43) | GPBAR1PRKCD | |
| SCHEMBL19129815 | 0.85 | GPBAR1 (0.43) | GPBAR1PRKCD | |
| SCHEMBL9891336 | 0.85 | GPBAR1 (0.57) | GPBAR1PRKCD | |
| SCHEMBL19129813 | 0.84 | GPBAR1 (0.54) | GPBAR1PRKCD | |
| SCHEMBL19129814 | 0.83 | GPBAR1 (0.51) | GPBAR1PRKCD | |
| SCHEMBL19129816 | 0.82 | TDP1 (0.37) | GPBAR1PRKCD | |
| SCHEMBL17380787 | 0.82 | GPBAR1 (0.44) | GPBAR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920090-B2 | Betulinic acid derivatives with HIV maturation inhibitory activity | VIIV Healthcare UK (No.5) Limited (GB) | 2018-03-20 | — | — | US | disclosed |
| US-20170204133-A1 | BETULINIC ACID DERIVATIVES WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204133-A1 | BETULINIC ACID DERIVATIVES WITH HIV MATURATION INHIBITORY ACTIVITY | BET1, PGGT1B, TMPO | GPBAR1 1377/4885PRKCD 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.