⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111205 | 0.82 | — | — | |
| SCHEMBL167375 | 0.81 | — | — | |
| SCHEMBL1665122 | 0.80 | PTGS1 (0.33) | — | |
| SCHEMBL9098275 | 0.76 | CYP1A2 (0.35) | — | |
| SCHEMBL9099217 | 0.76 | — | — | |
| SCHEMBL115827 | 0.74 | — | — | |
| SCHEMBL582917 | 0.72 | — | — | |
| SCHEMBL10934775 | 0.71 | PTGS1 (0.32) | — | |
| SCHEMBL17530124 | 0.68 | PTGS1 (0.31) | — | |
| SCHEMBL6064260 | 0.67 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187558-B1 | MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2021-03-24 | — | — | EP | claimed |
| US-9714315-B2 | Moisture curable silylated polymer compositions containing reactive modifiers | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-07-25 | — | — | US | claimed |
| US-9512104-B2 | Quinolone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |