Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 9/20 | 0.45 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691456 | 1.00 | CYP2D6 (0.54) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL20741877 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL8824639 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL26101291 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL26445366 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL20741964 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL25084117 | 0.92 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL7151952 | 0.92 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL7147587 | 0.92 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL29865303 | 0.92 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708607-B2 | Modified RNAi agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |