Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19133294 | 0.91 | ALK (0.81) | ALK | |
| SCHEMBL19133370 | 0.90 | ALK (0.79) | ALK | |
| SCHEMBL19133256 | 0.89 | ALK (0.77) | ALK | |
| SCHEMBL19133275 | 0.88 | ALK (0.80) | ALK | |
| SCHEMBL19133287 | 0.88 | ALK (0.80) | ALK | |
| SCHEMBL16346097 | 0.88 | ALK (1.00) | ALK | |
| SCHEMBL18830516 | 0.87 | ALK (0.75) | ALK | |
| SCHEMBL12601800 | 0.87 | ALK (0.77) | ALK | |
| SCHEMBL18058259 | 0.87 | ALK (0.79) | ALK | |
| SCHEMBL16346619 | 0.85 | ALK (1.00) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708279-B2 | 2-acylaminothiazoles for the treatment of cancer | UNIVERSITÁ DEGLI STUDI DI MILANO—BICOCCA (IT) | 2017-07-18 | — | — | US | disclosed |