Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159716 | 0.90 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1292452 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1281995 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL2739819 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL15260119 | 0.88 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL16975435 | 0.88 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL2739706 | 0.88 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL2739672 | 0.88 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL16975437 | 0.88 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1282410 | 0.88 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828257-B1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD (GB) | 2017-07-26 | — | — | EP | claimed |