SCHEMBL19136641

SCHEMBL19136641

CN(C)c1ccc(C=C2C(=O)c3ccccc3C2=C(C#N)C#N)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
MAPT P10636 12/20 0.49
APP P05067 8/20 0.49
SNCA P37840 8/20 0.49
ALDH1A1 P00352 7/20 0.49
MAPK1 P28482 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
PDGFRB P09619 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
GMNN O75496 1/20 0.49
LMNA P02545 1/20 0.49
HPGD P15428 1/20 0.49
MTOR P42345 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19136640 1.00 MIF (0.54) MIFMAPTAPPSNCAALDH1A1
SCHEMBL19136691 0.91 MAPT (0.48) MIFMAPTAPPSNCAALDH1A1
SCHEMBL23515521 0.89 LCK (0.47) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL12776339 0.87 LCK (0.40) MIFMAPTAPPSNCAALDH1A1
SCHEMBL23515582 0.87 LCK (0.40) MIFMAPTAPPSNCAALDH1A1
SCHEMBL20824923 0.86 KMT2A (0.44) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL23515524 0.85 LCK (0.44) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL24129947 0.85 KMT2A (0.47) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL27237569 0.85 KMT2A (0.47) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL34475190 0.85 MAPT (0.40) MIFMAPTAPPSNCAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4383990-A1 MATERIALS FOR OPTOELECTRONIC APPLICATIONS The Regents Of The University Of Michigan (US) 2024-06-12 EP disclosed
CN-118165006-A Materials for photovoltaic applications 密西根大学董事会 2024-06-11 CN disclosed
US-20170209373-A1 MULTIFUNCTIONAL POLYMERIC NANOPARTICLE FOR DIAGNOSIS OR TREATMENT OF CEREBRAL DISEASES AND A PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-07-27 US disclosed