Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136711 | 0.86 | MAPT (0.47) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL19136712 | 0.86 | MAPT (0.47) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL19179147 | 0.86 | MAPT (0.47) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL11070467 | 0.83 | MAPK1 (0.51) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL5369170 | 0.83 | MAPK1 (0.51) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL5369169 | 0.83 | MAPK1 (0.51) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL15101180 | 0.81 | MAPK1 (0.49) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL11669656 | 0.80 | MAPK1 (0.50) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL10623289 | 0.80 | MAPK1 (0.48) | MAPK1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL11669664 | 0.80 | MAPK1 (0.50) | MAPK1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209373-A1 | MULTIFUNCTIONAL POLYMERIC NANOPARTICLE FOR DIAGNOSIS OR TREATMENT OF CEREBRAL DISEASES AND A PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-07-27 | — | — | US | disclosed |
| US-20170209373-A1 | MULTIFUNCTIONAL POLYMERIC NANOPARTICLE FOR DIAGNOSIS OR TREATMENT OF CEREBRAL DISEASES AND A PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-07-27 | — | — | US | disclosed |