Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1914237 | 1.00 | MEN1 (0.32) | MEN1KMT2ATSHRGAA | |
| SCHEMBL13505203 | 0.85 | MEN1 (0.33) | MEN1KMT2AGAA | |
| SCHEMBL2449557 | 0.85 | MEN1 (0.33) | MEN1KMT2AGAA | |
| SCHEMBL1914667 | 0.85 | MEN1 (0.33) | MEN1KMT2AGAA | |
| SCHEMBL12332960 | 0.82 | PARP1 (0.33) | MEN1KMT2A | |
| SCHEMBL15349950 | 0.78 | KMT2A (0.39) | MEN1KMT2AGAA | |
| SCHEMBL2451203 | 0.78 | KDM4C (0.30) | — | |
| SCHEMBL1914099 | 0.77 | — | — | |
| SCHEMBL13505400 | 0.76 | HTR2B (0.36) | GAA | |
| SCHEMBL6126797 | 0.76 | HTR2B (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515902-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | Vertex Pharmaceuticals Incorporated (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079327-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-30 | — | — | WO | disclosed |