Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19142401 | 0.91 | ESR1 (0.46) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL19142413 | 0.90 | ESR1 (0.45) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL19143020 | 0.90 | RECQL (0.41) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL9611839 | 0.89 | ESR1 (0.50) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL9976973 | 0.85 | ESR1 (0.46) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL9611846 | 0.84 | ESR1 (0.45) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL9611843 | 0.84 | ESR1 (0.47) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL19142308 | 0.83 | ESR1 (0.36) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL12912480 | 0.82 | ESR1 (0.48) | ESR1ESR2GAAMEN1KMT2A | |
| SCHEMBL9611829 | 0.82 | ESR1 (0.50) | ESR1ESR2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192789-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |