Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18521980 | 1.00 | KDM4E (0.71) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL10068104 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL12714741 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL264546 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL20346237 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL264545 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL25507075 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL25797554 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL25504733 | 0.90 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1PNP | |
| SCHEMBL18521398 | 0.89 | KDM4E (0.71) | KDM4EPOLA1TAS1R3TAS1R1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117739-A1 | PROCESS FOR THE PREPARATION OF A CYCLIC DINUCLEOTIDE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |