Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.74 |
| ▸ | EGFR | P00533 | 1/20 | 0.73 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149030 | 1.00 | BTK (0.74) | BTKEGFRLCK | |
| SCHEMBL19149789 | 0.89 | BTK (0.81) | BTKEGFRLCK | |
| SCHEMBL19149790 | 0.89 | BTK (0.81) | BTKEGFRLCK | |
| SCHEMBL19150688 | 0.89 | BTK (0.67) | BTKEGFRLCK | |
| SCHEMBL19150689 | 0.89 | BTK (0.67) | BTKEGFRLCK | |
| SCHEMBL19148587 | 0.88 | BTK (0.71) | BTKEGFRLCK | |
| SCHEMBL22018928 | 0.88 | EGFR (0.79) | BTKEGFRLCK | |
| SCHEMBL28691174 | 0.88 | BTK (0.71) | BTKEGFRLCK | |
| SCHEMBL19149014 | 0.88 | BTK (0.68) | BTKEGFRLCK | |
| SCHEMBL19149013 | 0.88 | BTK (0.68) | BTKEGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405192-B1 | BRUTON'S TYROSINE KINASE INHIBITORS | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO LTD (CN) | 2024-12-11 | — | — | EP | disclosed |
| CN-109310671-B | Bruton's tyrosine kinase inhibitors | 淄博百极常生制药有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-10793566-B2 | Bruton's tyrosine kinase inhibitors | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD. (CN) | 2020-10-06 | — | — | US | disclosed |
| US-10793566-B2 | Bruton's tyrosine kinase inhibitors | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD. (CN) | 2020-10-06 | — | — | US | disclosed |
| US-10662187-B2 | Bruton's tyrosine kinase inhibitors | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-10662187-B2 | Bruton's tyrosine kinase inhibitors | ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20190276453-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2019-09-12 | — | — | US | disclosed |
| US-20190276453-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2019-09-12 | — | — | US | disclosed |
| EP-3405192-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | Zibo Biopolar Changsheng Pharmaceutical Co. Ltd. (CN) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017127371-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | SUNNYLIFE PHARMA INC. (US) | 2017-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662187-B2 | Bruton's tyrosine kinase inhibitors | BTK, ABL1, SYK | BTK 1/4885EGFR 210/4885LCK 5/4885 |
| US-10793566-B2 | Bruton's tyrosine kinase inhibitors | BTK, ABL1, SYK | BTK 1/4885EGFR 210/4885LCK 5/4885 |
| US-20190276453-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BTK, ABL1, SYK | BTK 1/4885EGFR 210/4885LCK 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.