Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148219 | 0.89 | ADORA2A (0.42) | IGF1RNT5EADORA2AADORA1NPC1 | |
| SCHEMBL19150076 | 0.86 | NT5E (0.54) | NT5EADORA2AADORA1LMNATP53 | |
| SCHEMBL19148196 | 0.84 | DHODH (0.42) | NPC1RAB9ASCN5AGMNNUSP2 | |
| SCHEMBL2855628 | 0.81 | NT5E (0.60) | IGF1RNT5ENPC1RAB9ASCN5A | |
| SCHEMBL2854016 | 0.79 | IGF1R (0.48) | IGF1RNT5EADORA2AADORA1NPC1 | |
| SCHEMBL19148211 | 0.79 | NT5E (0.47) | NT5EADORA2AADORA1TP53SMN1; SMN2 | |
| SCHEMBL16832212 | 0.76 | DHODH (0.56) | IGF1RNT5ELMNATP53CYP1A2 | |
| SCHEMBL19150082 | 0.75 | ADORA2A (0.68) | IGF1RNT5EADORA2AADORA1GAA | |
| SCHEMBL19148559 | 0.74 | ADORA2A (0.42) | NT5EADORA2AADORA1SMN1; SMN2TLR7 | |
| SCHEMBL19148578 | 0.74 | NT5E (0.48) | NT5EADORA2AADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| EP-3405458-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | Bayer CropScience Aktiengesellschaft (DE) | 2018-11-28 | — | — | EP | disclosed |
| CN-108473433-A | The method for preparing the quinoline of Polyfluoroalkyl | 拜耳作物科学股份公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2017125318-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | KCNQ1, KCNQ2, KCNQ4 | IGF1R 4658/4885NT5E 1186/4885ADORA2A 2373/4885 |
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | KCNQ1, KCNQ2, KCNQ4 | IGF1R 4658/4885NT5E 1186/4885ADORA2A 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.