Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739231 | 0.95 | FFAR1 (0.74) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL17249855 | 0.94 | FFAR1 (0.81) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL20043116 | 0.93 | FFAR1 (0.74) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL17239704 | 0.92 | FFAR1 (0.79) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19154644 | 0.90 | FFAR1 (0.64) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19154753 | 0.88 | FFAR1 (0.69) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19154759 | 0.88 | FFAR1 (0.69) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL17249853 | 0.87 | FFAR1 (0.81) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL17249854 | 0.87 | FFAR1 (0.81) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL15739119 | 0.86 | FFAR1 (0.75) | FFAR1CYP3A4CYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714231-B2 | Pyrrolidine GPR40 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | disclosed |