Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16064299 | 0.92 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL19155342 | 0.90 | CTSC (0.56) | CTSCCTSK | |
| SCHEMBL19155036 | 0.89 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL19155097 | 0.88 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19368416 | 0.88 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19155039 | 0.88 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19368351 | 0.88 | CTSC (0.40) | CTSCCTSK | |
| SCHEMBL19155308 | 0.87 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL19155091 | 0.86 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL22642959 | 0.86 | CTSC (0.61) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9713606-B2 | Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-07-25 | — | — | US | disclosed |