Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.61 |
| ▸ | CTSK | P43235 | 15/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076206 | 1.00 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL19155334 | 1.00 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL19155322 | 0.94 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL19361425 | 0.92 | CTSC (0.68) | CTSCCTSK | |
| SCHEMBL16064253 | 0.92 | CTSC (0.68) | CTSCCTSK | |
| SCHEMBL21076203 | 0.89 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL21076205 | 0.89 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL22643265 | 0.89 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19155136 | 0.89 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL19155066 | 0.89 | CTSC (0.58) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9713606-B2 | Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-07-25 | — | — | US | disclosed |