Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19529036 | 1.00 | TLR2 (0.48) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL21597893 | 0.91 | TLR2 (0.57) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL29401420 | 0.91 | TLR2 (0.57) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL29368615 | 0.91 | TLR2 (0.57) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL13227673 | 0.91 | TLR2 (0.57) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL12568245 | 0.91 | TLR2 (0.57) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL17790570 | 0.89 | KMT2A (0.56) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL12108058 | 0.89 | MDM2 (0.47) | TLR2MDM4TP53CASP3MDM2 | |
| SCHEMBL13996828 | 0.89 | TLR2 (0.49) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL12681417 | 0.88 | PTPN1 (0.50) | TLR2MDM4TP53CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612857-B1 | CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE | SHENZHEN SALUBRIS PHARM CO LTD (CN) | 2017-07-26 | — | — | EP | disclosed |