Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 8/20 | 0.76 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598896 | 0.86 | VEGFA (1.00) | VEGFAEGLN1KMT2ALMNAALDH1A1 | |
| SCHEMBL17005957 | 0.86 | VEGFA (0.61) | VEGFAEGLN1POLBKMT2ACYP2A13 | |
| SCHEMBL16790919 | 0.85 | VEGFA (0.80) | VEGFAEGLN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12598836 | 0.85 | VEGFA (0.76) | VEGFAEGLN1POLBCYP2A13ALDH1A1 | |
| SCHEMBL12598835 | 0.85 | VEGFA (0.97) | VEGFAEGLN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1773790 | 0.84 | VEGFA (0.71) | VEGFAEGLN1KMT2ALMNAACHE | |
| SCHEMBL273696 | 0.83 | EGLN1 (0.85) | VEGFAEGLN1LMNAKDM4E | |
| SCHEMBL271963 | 0.83 | EGLN1 (0.85) | VEGFAEGLN1LMNAKDM4E | |
| SCHEMBL277668 | 0.83 | EGLN1 (0.85) | VEGFAEGLN1LMNAKDM4E | |
| SCHEMBL17005914 | 0.83 | VEGFA (0.55) | VEGFAEGLN1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3603644-A1 | PROLYL HYDROXYLASE INHIBITORS | Aerpio Therapeutics, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| EP-2853265-B1 | Methods for increasing the stabilization of hypoxia inducible factor-1 alpha | AERPIO THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |