Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.73 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.73 |
| ▸ | ITGAL | P20701 | 20/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158046 | 0.90 | ITGB2 (0.76) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL4755977 | 0.85 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756097 | 0.83 | ITGB2 (0.78) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL19158574 | 0.82 | ITGB2 (0.73) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL4756017 | 0.81 | ITGB2 (0.73) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL19158066 | 0.81 | ITGB2 (0.73) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL879369 | 0.81 | ITGB2 (1.00) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18867992 | 0.81 | ITGB2 (0.79) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868034 | 0.81 | ITGB2 (0.79) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL4755889 | 0.81 | ITGB2 (0.81) | ITGB2ICAM1ITGALCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195861-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DRY EYE DISORDERS | SARcode Bioscience Inc. (US) | 2017-07-26 | — | — | EP | disclosed |