Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 11/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.33 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153584 | 0.95 | ITGAL (0.62) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL12169811 | 0.95 | ITGAL (0.62) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL19157868 | 0.95 | ITGAL (0.62) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL17991456 | 0.95 | ITGAL (0.62) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL18885625 | 0.87 | ITGAL (0.60) | ITGALITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL17991450 | 0.87 | ITGAL (0.57) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL12169805 | 0.86 | ITGAL (0.58) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL17991432 | 0.86 | ITGAL (0.58) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL22296921 | 0.86 | ITGAL (0.58) | ITGALITGB2ICAM1ITGB1ITGA4 | |
| SCHEMBL4756091 | 0.86 | ITGAL (0.58) | ITGALITGB2ICAM1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195861-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DRY EYE DISORDERS | SARcode Bioscience Inc. (US) | 2017-07-26 | — | — | EP | disclosed |