Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559840 | 0.96 | POLB (0.40) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL19158316 | 0.93 | POLB (0.42) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL17538614 | 0.93 | POLB (0.43) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL22023580 | 0.91 | POLB (0.37) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL16573113 | 0.91 | POLB (0.45) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL20275179 | 0.90 | POLB (0.36) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL23350596 | 0.89 | POLB (0.36) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL21675468 | 0.89 | POLB (0.36) | FFAR1POLBAPEX1HTTTDP1 | |
| SCHEMBL24440805 | 0.88 | KDM4E (0.39) | POLBAPEX1HTTTDP1RARG | |
| SCHEMBL20275159 | 0.88 | POLB (0.36) | FFAR1POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |