Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17503813 | 0.77 | MCL1 (0.42) | KDM4CKDM5AKDM5BKDM4EMEN1 | |
| SCHEMBL17503689 | 0.77 | CYP2D6 (0.38) | KDM4CKDM5AKDM5BMEN1KMT2A | |
| SCHEMBL16128631 | 0.76 | KDM4C (0.34) | KDM4CKDM5AKDM5BLTA4H | |
| SCHEMBL16128867 | 0.76 | KDM5A (0.34) | KDM4CKDM5AKDM5BKDM4EMAPT | |
| SCHEMBL17503762 | 0.72 | KDM5A (0.49) | KDM4CKDM5AKDM5B | |
| SCHEMBL17503744 | 0.70 | KDM2B (0.39) | KDM4CKDM5AKDM5B | |
| SCHEMBL17503843 | 0.68 | KDM4C (0.41) | KDM4CKDM5AKDM5B | |
| SCHEMBL17503790 | 0.67 | KDM5B (0.36) | KDM4CKDM5AKDM5B | |
| SCHEMBL17503804 | 0.67 | KDM4C (0.41) | KDM4CKDM5AKDM5BKDM4E | |
| SCHEMBL17503779 | 0.67 | KDM5B (0.41) | KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |