Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.48 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.41 |
| ▸ | LATS1 | O95835 | 11/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158856 | 0.84 | KDM4C (0.40) | KDM4CHASPINLATS1LATS2CXCR2 | |
| SCHEMBL19159293 | 0.83 | KDM4C (0.40) | KDM4CHASPINLATS1LATS2CXCR2 | |
| SCHEMBL19158323 | 0.83 | KDM4C (0.44) | KDM4CHASPINLATS1LATS2 | |
| SCHEMBL19158955 | 0.81 | KDM4C (0.38) | KDM4CHASPINLATS1LATS2CXCR2 | |
| SCHEMBL19159126 | 0.79 | KDM4C (0.40) | KDM4CLATS1LATS2 | |
| SCHEMBL19158841 | 0.78 | KDM4C (0.39) | KDM4CHASPINLATS1LATS2KDM4E | |
| SCHEMBL19158337 | 0.73 | KDM4C (0.46) | KDM4CLATS1LATS2 | |
| SCHEMBL19159277 | 0.70 | KDM4C (0.43) | KDM4CLATS1LATS2KDM4E | |
| SCHEMBL4863823 | 0.70 | ABCB1 (0.43) | KDM4EMAPK1 | |
| SCHEMBL19158347 | 0.70 | KDM4C (0.42) | KDM4CLATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |