Genistein

Genistein

SCHEMBL19166

O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
SMN1; SMN2 Q16637 7/20 1.00
ALDH1A1 P00352 7/20 1.00
RAB9A P51151 7/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
TP53 P04637 6/20 1.00
HPGD P15428 6/20 1.00
NPC1 O15118 6/20 1.00
ALOX15 P16050 5/20 1.00
CYP3A4 P08684 4/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2C19 P33261 4/20 1.00
HSD17B2 P37059 3/20 1.00
POLB P06746 3/20 1.00
MAPK1 P28482 3/20 1.00
AKR1B10 O60218 3/20 1.00
LMNA P02545 3/20 1.00
CYP19A1 P11511 3/20 1.00
MAOA P21397 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Genistein SCHEMBL554056 1.00 MAPT (1.00) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL29352944 1.00 MAPT (1.00) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL31168045 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL551402 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL551801 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL551449 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL29586842 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL551352 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL38650814 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1
Genistein SCHEMBL29586487 0.98 MAPT (0.97) MAPTSMN1; SMN2ALDH1A1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 51116 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075533-A S-equol composition for delaying ovarian aging and application thereof 2026-05-26 CN claimed
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
CN-122081128-A Lactobacillus rhamnosus and application thereof 2026-05-26 CN claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
CN-122031592-A Application of dragon's blood and active ingredients thereof in preparation of drugs for treating heart failure 上海中医药大学 2026-05-15 CN claimed
CN-122033259-A Preparation method of low-dimensional silver nanostructure driven by dynamic polymer hydrogel 深圳市源利电子新材料有限公司 2026-05-15 CN claimed
WO-2026099270-A1 BIODEGRADABLE UV ABSORBERS AND USES THEREOF II BASF SE (DE) 2026-05-15 WO claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
US-5352384-A Aglucone isoflavone enriched vegetable protein fiber PROTEIN TECHNOLOGIES INTERNATIONAL, INC. (US) 1994-10-04 US claimed
EP-0595133-A2 Prodrugs, their preparation and use as medicaments BEHRINGWERKE Aktiengesellschaft (DE) 1994-05-04 EP claimed
WO-1993023069-A1 HEALTH SUPPLEMENTS CONTAINING PHYTO-OESTROGENS, ANALOGUES OR METABOLITES THEREOF KELLY GRAHAM EDMUND (AU) 1993-11-25 WO claimed
EP-0273771-B1 MUTAGENIC EVALUATION METHOD E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-22 EP claimed
US-5229113-A Gene expression, soybeans LUBRIZOL GENETICS, INC. (US) 1993-07-20 US claimed
US-5213971-A Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-25 US claimed
EP-0269725-A4 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE. LUBRIZOL GENETICS INC (US) 1989-01-12 EP claimed
EP-0273771-A2 Mutagenic evaluation method E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP claimed
EP-0269725-A1 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE LUBRIZOL GENETICS INC. (US) 1988-06-08 EP claimed
WO-1987007910-A1 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE LUBRIZOL GENETICS, INC. (US) 1987-12-30 WO claimed