Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19168879 | 1.00 | PDK2 (0.35) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL24750395 | 0.99 | PDK2 (0.36) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL24647072 | 0.99 | PDK2 (0.36) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL24646699 | 0.99 | PDK2 (0.36) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL15213630 | 0.99 | PDK2 (0.36) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL24750858 | 0.99 | PDK2 (0.36) | PDK2MEN1LMNAMAPTKMT2A | |
| SCHEMBL21559025 | 0.97 | PDK2 (0.35) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21922838 | 0.97 | PDK2 (0.37) | PDK2MAPTL3MBTL1MLNRNR1I2 | |
| SCHEMBL21922840 | 0.97 | PDK2 (0.37) | PDK2MAPTL3MBTL1MLNRNR1I2 | |
| SCHEMBL19011253 | 0.97 | PDK2 (0.35) | PDK2MLNRNR1I2CHRM2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10424744-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-09-24 | — | — | US | disclosed |
| US-20170213971-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
| US-20170213971-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10424744-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | PDK2 2514/4885MEN1 305/4885APAF1 3170/4885 |
| US-20170213971-A1 | Novel compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | PDK2 2806/4885MEN1 251/4885APAF1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.