Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19168452 | 0.93 | HDAC6 (0.67) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19161683 | 0.92 | HDAC6 (0.78) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19168853 | 0.92 | HDAC6 (0.65) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19168863 | 0.90 | HDAC6 (0.66) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19169206 | 0.89 | HDAC6 (0.67) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19168900 | 0.89 | HDAC6 (0.85) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19168055 | 0.88 | HDAC6 (0.64) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19168887 | 0.86 | HDAC6 (0.54) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19139012 | 0.85 | HDAC6 (0.78) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL19161145 | 0.85 | HDAC6 (0.78) | HDAC6HDAC1HDAC2HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | HDAC6, HDAC5, HDAC4 | HDAC6 1/4885HDAC1 4/4885HDAC2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.