Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31718049 | 0.85 | PTPN1 (0.55) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL2876805 | 0.85 | NR4A1 (0.61) | PARP1NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL2343264 | 0.85 | GRIN2D (0.61) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL10012830 | 0.85 | GRIN2D (0.61) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL19177351 | 0.85 | GRIN2D (0.61) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL28539627 | 0.81 | NR4A1 (0.61) | PARP1NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL31500205 | 0.79 | PTPN1 (0.67) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL30812 | 0.79 | PTPN1 (0.67) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL17254441 | 0.79 | TSHR (0.58) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 | |
| SCHEMBL31279968 | 0.79 | TSHR (0.58) | PTPN1GRIN2DGRIN2AGRIN2CPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611033-B1 | TIRE, AND METHOD FOR MANUFACTURING TIRE | BRIDGESTONE CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| EP-3266623-B1 | TIRE | BRIDGESTONE CORP (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-107405952-B | Tyre for vehicle wheels | 株式会社普利司通 | 2020-06-02 | — | — | CN | disclosed |
| US-20200130413-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2020-04-30 | — | — | US | disclosed |
| US-20200061979-A1 | TIRE, AND METHOD FOR MANUFACTURING TIRE | BRIDGESTONE CORPORATION (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3611033-A1 | TIRE, AND METHOD FOR MANUFACTURING TIRE | Bridgestone Corporation (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-3513989-A1 | TIRE | Bridgestone Corporation (JP) | 2019-07-24 | — | — | EP | disclosed |
| US-20190202239-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2019-07-04 | — | — | US | disclosed |
| EP-3199571-B1 | TIRE | BRIDGESTONE CORP (JP) | 2019-06-05 | — | — | EP | disclosed |
| EP-3486095-A1 | TIRE | Bridgestone Corporation (JP) | 2019-05-22 | — | — | EP | disclosed |
| US-20180050565-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2018-02-22 | — | — | US | disclosed |
| EP-3266623-A1 | TIRE | Bridgestone Corporation (JP) | 2018-01-10 | — | — | EP | disclosed |
| US-20170298182-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3199571-A1 | TIRE | Bridgestone Corporation (JP) | 2017-08-02 | — | — | EP | disclosed |