SCHEMBL19178264

SCHEMBL19178264

CCN(C)c1nc2c(cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)ncn2CC

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16969503 0.87 CETP (0.39) CETP
SCHEMBL16969489 0.86 CETP (0.35) CETP
SCHEMBL5624234 0.86 CETP (0.35) CETP
SCHEMBL5626462 0.86 CETP (0.36) CETP
SCHEMBL6101367 0.84 CETP (0.35) CETP
SCHEMBL19178333 0.84 CETP (0.35) CETP
SCHEMBL16969501 0.83 CETP (0.35) CETP
SCHEMBL5629586 0.83 CETP (0.35) CETP
SCHEMBL6091240 0.82 CETP (0.34) CETP
SCHEMBL5623788 0.82 CETP (0.36) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848430-B1 NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS Dr Reddys Laboratories Ltd (IN) 2017-08-02 EP disclosed