Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17687243 | 0.93 | ACKR3 (0.55) | ACKR3HRH3S1PR5ALDH1A1PRMT5 | |
| SCHEMBL16269320 | 0.90 | ACKR3 (0.53) | ACKR3CARM1ACACBS1PR5PRMT5 | |
| SCHEMBL17686913 | 0.89 | ACKR3 (0.67) | ACKR3HRH3CARM1ACACBS1PR5 | |
| SCHEMBL19177304 | 0.89 | ACKR3 (0.56) | ACKR3CARM1S1PR5ALDH1A1PRMT5 | |
| SCHEMBL17687062 | 0.88 | ACKR3 (0.58) | ACKR3HRH3ACACBPRMT5WDR77 | |
| SCHEMBL16269511 | 0.87 | ACKR3 (0.57) | ACKR3ALDH1A1TRPM8 | |
| SCHEMBL16269024 | 0.85 | ACKR3 (0.57) | ACKR3CARM1S1PR5PRMT5WDR77 | |
| SCHEMBL17687010 | 0.85 | ACKR3 (0.76) | ACKR3 | |
| SCHEMBL19178006 | 0.85 | ACKR3 (0.58) | ACKR3CARM1ACACBS1PR5ALDH1A1 | |
| SCHEMBL19177882 | 0.84 | ACKR3 (0.51) | ACKR3CARM1ACACBS1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004082-B1 | CXCR7 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-08-02 | — | — | EP | disclosed |