Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001698 | 0.90 | PARP1 (0.60) | PARP1 | |
| SCHEMBL15001728 | 0.90 | PARP1 (0.73) | PARP1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16215151 | 0.89 | PARP1 (0.72) | PARP1 | |
| SCHEMBL15002417 | 0.88 | PARP1 (0.58) | PARP1 | |
| SCHEMBL16207560 | 0.88 | PARP1 (0.72) | PARP1LMNAHPGDALDH1A1 | |
| SCHEMBL16215131 | 0.88 | PARP1 (0.73) | PARP1 | |
| SCHEMBL15002560 | 0.88 | PARP1 (0.74) | PARP1 | |
| SCHEMBL16215129 | 0.88 | PARP1 (0.67) | PARP1 | |
| SCHEMBL16207704 | 0.87 | PARP1 (0.56) | PARP1 | |
| SCHEMBL16207724 | 0.87 | PARP1 (0.58) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718787-B2 | Poly (ADP-ribose) polymerase inhibitor | CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD. (CN) | 2017-08-01 | — | — | US | disclosed |