Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | GJB2 | P29033 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | GJA1 | P17302 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371822 | 0.91 | NT5E (0.60) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL7215148 | 0.91 | NT5E (0.60) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL7215147 | 0.91 | NT5E (0.60) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL7174275 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL8227941 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL4185190 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL7174279 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL8222985 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL8227939 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 | |
| SCHEMBL18744566 | 0.90 | NT5E (0.59) | NT5EPTPN1CDC25BLMNASSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357931-B1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | SLOAN KETTERING INST CANCER RES (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
| US-9718850-B2 | Triterpene saponins, methods of synthesis and uses thereof | MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | NT5E 2902/4885GJB2 4372/4885PTPN1 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.