Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 17/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | GSK3A | P49840 | 8/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185978 | 0.94 | GSK3B (0.57) | GSK3BMAPTGSK3A | |
| SCHEMBL19186033 | 0.84 | GSK3B (0.66) | GSK3BMAPTGSK3A | |
| SCHEMBL16704301 | 0.80 | GSK3B (1.00) | GSK3BMAPTGSK3AATR | |
| SCHEMBL19185942 | 0.79 | MAPT (0.67) | GSK3BMAPTGSK3A | |
| SCHEMBL19186312 | 0.79 | MAPT (0.67) | GSK3BMAPTGSK3A | |
| SCHEMBL16702498 | 0.78 | GSK3B (0.68) | GSK3BMAPTGSK3AATRABL1 | |
| SCHEMBL18089233 | 0.76 | GSK3B (0.69) | GSK3BMAPTGSK3AATRABL1 | |
| SCHEMBL19186362 | 0.75 | GSK3B (0.43) | GSK3BMAPTGSK3A | |
| SCHEMBL16703325 | 0.73 | GSK3B (0.85) | GSK3BMAPTGSK3A | |
| SCHEMBL16702874 | 0.71 | GSK3B (0.61) | GSK3BMAPTGSK3AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718804-B2 | GSK-3 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-01 | — | — | US | disclosed |