Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.58 |
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | MMEL1 | Q495T6 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902429 | 0.91 | MME (0.72) | MMEACEMMEL1 | |
| SCHEMBL18597756 | 0.91 | MME (0.72) | MMEACEMMEL1 | |
| SCHEMBL19690456 | 0.84 | MME (0.63) | MMEACEMMEL1 | |
| SCHEMBL18724941 | 0.84 | MME (0.63) | MMEACEMMEL1 | |
| SCHEMBL19840282 | 0.84 | MME (0.63) | MMEACEMMEL1 | |
| SCHEMBL17011360 | 0.84 | MME (0.63) | MMEACEMMEL1 | |
| SCHEMBL19708727 | 0.83 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL19708546 | 0.82 | MME (0.48) | MMEACEMMEL1 | |
| SCHEMBL18724833 | 0.82 | MME (0.59) | MMEACEMMEL1 | |
| SCHEMBL17011370 | 0.82 | MME (0.59) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199517-A1 | NEPRILYSIN INHIBITORS | Theravance Biopharma R&D IP, LLC (US) | 2017-08-02 | — | — | EP | disclosed |