Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17444853 | 0.91 | PPARD (0.47) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211403 | 0.90 | PPARD (0.58) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL19190806 | 0.90 | PPARD (0.49) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL15211857 | 0.89 | PPARD (0.48) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17444885 | 0.85 | PPARD (0.47) | PPARDPPARAPPARGALDH1A1RAB9A | |
| SCHEMBL19192066 | 0.85 | PPARD (0.39) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17444893 | 0.85 | PPARD (0.41) | PPARDPPARAPPARGALDH1A1KDM4E | |
| SCHEMBL17444895 | 0.84 | PPARD (0.38) | PPARDPPARAPPARGALDH1A1MTNR1A | |
| SCHEMBL15220507 | 0.84 | PPARD (0.38) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17444856 | 0.84 | PPARD (0.49) | PPARDPPARAPPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-B1 | AROMATIC RING COMPOUND AS GHRELIN O-ACYLTRANSFERASE INHIBITOR | TAKEDA PHARMACEUTICALS CO (JP) | 2017-08-02 | — | — | EP | disclosed |