Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692753 | 1.00 | IDH1 (0.45) | IDH1MTOR | |
| SCHEMBL19692754 | 1.00 | IDH1 (0.45) | IDH1MTOR | |
| SCHEMBL19179094 | 0.82 | IDH1 (0.58) | IDH1 | |
| SCHEMBL19692705 | 0.82 | IDH1 (0.48) | IDH1MTOR | |
| SCHEMBL14831089 | 0.82 | IDH1 (0.64) | IDH1 | |
| SCHEMBL19692706 | 0.82 | IDH1 (0.48) | IDH1MTOR | |
| SCHEMBL14831090 | 0.82 | IDH1 (0.64) | IDH1 | |
| SCHEMBL14846751 | 0.82 | IDH1 (0.58) | IDH1 | |
| SCHEMBL30324889 | 0.80 | IDH1 (0.57) | IDH1 | |
| SCHEMBL16043882 | 0.80 | IDH1 (0.48) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771337-B1 | 3-(PYRIMIDIN-4-YL)-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH | NOVARTIS AG (CH) | 2017-08-02 | — | — | EP | disclosed |