Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.75 |
| ▸ | BCR | P11274 | 11/20 | 0.75 |
| ▸ | LYN | P07948 | 2/20 | 0.75 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.70 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | PRKCA | P17252 | 1/20 | 0.68 |
| ▸ | KIT | P10721 | 3/20 | 0.67 |
| ▸ | ABL2 | P42684 | 2/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3568536 | 0.94 | ABL1 (0.73) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL3566747 | 0.94 | ABL1 (0.75) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL28755616 | 0.88 | ABL1 (0.80) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL3568761 | 0.88 | ABL1 (0.89) | ABL1BCRLYNPDGFRAPDGFRB | |
| Diethylamine SCHEMBL3568539 | 0.87 | PDGFRA (0.74) | ABL1BCRLYNPDGFRAPDGFRB | |
| Dimethylamine SCHEMBL3566750 | 0.87 | ABL1 (0.79) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL13157377 | 0.87 | ABL1 (0.81) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL3563459 | 0.86 | ABL1 (1.00) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL3562697 | 0.86 | ABL1 (0.89) | ABL1BCRLYNPDGFRAPDGFRB | |
| SCHEMBL3561315 | 0.85 | ABL1 (0.88) | ABL1BCRLYNPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702917-B1 | AMIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2017-08-02 | — | — | EP | disclosed |