Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934035 | 0.89 | PDE9A (0.56) | PDE9A | |
| SCHEMBL6340015 | 0.87 | PDE9A (0.54) | PDE9A | |
| SCHEMBL6339138 | 0.87 | PDE9A (0.66) | PDE9A | |
| SCHEMBL6342877 | 0.86 | PDE9A (0.56) | PDE9A | |
| SCHEMBL6341968 | 0.85 | PDE9A (0.62) | PDE9A | |
| SCHEMBL6339235 | 0.85 | PDE9A (0.64) | PDE9A | |
| SCHEMBL6339180 | 0.84 | PDE9A (0.64) | PDE9A | |
| SCHEMBL7934026 | 0.83 | PDE9A (0.61) | PDE9A | |
| SCHEMBL6339305 | 0.83 | PDE9A (0.67) | PDE9A | |
| SCHEMBL6339629 | 0.82 | PDE9A (0.55) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334684-B1 | PYRAZOLOPYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CNS DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |