Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884418 | 0.85 | PDE9A (0.66) | PDE9APDE1C | |
| SCHEMBL6339076 | 0.83 | PDE9A (0.57) | PDE9APDE1C | |
| SCHEMBL6343967 | 0.81 | PDE9A (0.66) | PDE9APDE1C | |
| SCHEMBL7885778 | 0.80 | PDE9A (0.68) | PDE9APDE1C | |
| SCHEMBL6342509 | 0.79 | PDE9A (0.79) | PDE9APDE1C | |
| SCHEMBL6340000 | 0.79 | PDE9A (0.83) | PDE9APDE1C | |
| SCHEMBL16900030 | 0.77 | PDE9A (0.55) | PDE9APDE1C | |
| SCHEMBL7887071 | 0.76 | PDE9A (0.62) | PDE9APDE1C | |
| SCHEMBL6343941 | 0.74 | PDE9A (0.82) | PDE9APDE1C | |
| SCHEMBL6341134 | 0.74 | PDE9A (0.61) | PDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334684-B1 | PYRAZOLOPYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CNS DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |