SCHEMBL1919360

SCHEMBL1919360

COC(N)CCS(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
APP P05067 1/20 0.36
S1PR2 O95136 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
TP53 P04637 1/20 0.33
ENPEP Q07075 4/20 0.33
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920398 0.76
SCHEMBL28980311 0.76 PTGS1 (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28137092 0.76 PTGS1 (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL766601 0.74 PTGS1 (0.35) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL766602 0.74 PTGS1 (0.35) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL20528290 0.74 PMP22 (0.38) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL356494 0.73
SCHEMBL21623887 0.73
SCHEMBL11489923 0.73 PTGS1 (0.33) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL15770527 0.73 PTGS1 (0.33) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2326619-A2 METHIONINE ANALOGS AND METHODS OF USING SAME Bioxiness Pharmaceuticals, Inc. (US) 2011-06-01 EP disclosed
WO-2010014943-A2 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICS, INC. (US) 2010-02-04 WO disclosed