Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194830 | 0.90 | KCNH2 (0.67) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL20590182 | 0.90 | KCNH2 (0.67) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL20590181 | 0.90 | KCNH2 (0.67) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL17494478 | 0.89 | KCNH2 (0.66) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL19200423 | 0.89 | SCN5A (0.53) | KCNH2SCN5AALDH1A1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL17494482 | 0.89 | KCNH2 (0.66) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL19200553 | 0.89 | SCN5A (0.66) | KCNH2SCN5A | |
| SCHEMBL19200407 | 0.89 | SCN5A (0.66) | KCNH2SCN5A | |
| SCHEMBL17494448 | 0.88 | KCNH2 (0.49) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL17494445 | 0.88 | KCNH2 (0.49) | KCNH2SCN5AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | WUXI APPTEC (CN) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | TOP1, NQO2, TOP2A | KCNH2 3467/4885SCN5A 1288/4885KDM4E 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.