Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183414 | 1.00 | KDM4D (0.39) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19200379 | 0.88 | GRM7 (0.46) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19200378 | 0.88 | GRM7 (0.46) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL20678677 | 0.88 | GRM7 (0.41) | GRM7GHSRKCNH2KCNQ2PYGL | |
| SCHEMBL19200429 | 0.87 | GRM7 (0.47) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19200308 | 0.87 | GRM7 (0.47) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19200428 | 0.87 | GRM7 (0.47) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19200466 | 0.83 | KDM4D (0.42) | KDM4DGRM7SCN9AGHSRMAPK14 | |
| SCHEMBL19200269 | 0.83 | KDM4D (0.42) | KDM4DGRM7SCN9AGHSRKCNH2 | |
| SCHEMBL19183522 | 0.82 | KDM4D (0.38) | KDM4DGRM7SCN9AGHSREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131221-A1 | INDANE DERIVATIVES AS MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-03 | — | — | WO | disclosed |