Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.55 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | TXK | P42681 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194829 | 0.87 | SCN5A (0.68) | SCN5AKCNH2 | |
| SCHEMBL19195294 | 0.86 | SCN5A (0.70) | SCN5AKCNH2 | |
| SCHEMBL17494378 | 0.86 | SCN5A (0.58) | SCN5AKCNH2BTKEGFRTEC | |
| Hydrochloric Acid SCHEMBL17494242 | 0.85 | SCN5A (0.69) | SCN5AKCNH2 | |
| SCHEMBL19200553 | 0.83 | SCN5A (0.66) | SCN5AKCNH2 | |
| SCHEMBL19200407 | 0.83 | SCN5A (0.66) | SCN5AKCNH2 | |
| SCHEMBL19200476 | 0.83 | SCN5A (0.66) | SCN5AKCNH2 | |
| SCHEMBL19194828 | 0.83 | SCN5A (0.73) | SCN5AKCNH2 | |
| SCHEMBL19194871 | 0.82 | SCN5A (0.75) | SCN5AKCNH2 | |
| SCHEMBL19194740 | 0.81 | SCN5A (0.68) | SCN5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | WUXI APPTEC (CN) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217897-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | TOP1, NQO2, TOP2A | SCN5A 1288/4885KCNH2 3467/4885BTK 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.