Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | OXTR | P30559 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183091 | 1.00 | KDM4D (0.41) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200374 | 0.92 | KDM4D (0.40) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200269 | 0.92 | KDM4D (0.42) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200466 | 0.89 | KDM4D (0.42) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200379 | 0.85 | GRM7 (0.46) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200378 | 0.85 | GRM7 (0.46) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200515 | 0.85 | GRM7 (0.40) | KDM4DGRM7GHSROXTRCYP3A4 | |
| SCHEMBL19182901 | 0.85 | GRM7 (0.40) | KDM4DGRM7GHSROXTRCYP3A4 | |
| SCHEMBL19183522 | 0.85 | KDM4D (0.38) | KDM4DGRM7GHSRSCN9AOXTR | |
| SCHEMBL19200479 | 0.83 | KDM4D (0.37) | KDM4DGRM7GHSRSCN9AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131221-A1 | INDANE DERIVATIVES AS MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-03 | — | — | WO | disclosed |