Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 20/20 | 0.82 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.82 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.82 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663849 | 0.93 | S1PR3 (0.85) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664134 | 0.93 | S1PR3 (0.85) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17663918 | 0.92 | S1PR3 (0.84) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664144 | 0.90 | S1PR3 (1.00) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664417 | 0.90 | S1PR3 (0.82) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664399 | 0.90 | S1PR3 (0.91) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664149 | 0.88 | S1PR3 (0.77) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664397 | 0.88 | S1PR3 (0.77) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL17664147 | 0.88 | S1PR3 (0.83) | S1PR3S1PR1S1PR5S1PR4 | |
| SCHEMBL19195266 | 0.88 | S1PR3 (0.83) | S1PR3S1PR1S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034691-B2 | Sphinogosine-1 -phosphate receptor modulators for treatment of cardiopulmonary disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-15 | — | — | US | disclosed |
| US-20190300527-A1 | SPHINOGOSINE-1-PHOSPHATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-03 | — | — | US | disclosed |
| US-10323029-B2 | Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-06-18 | — | — | US | disclosed |
| US-20170217963-A1 | SPHINOGOSINE-1-PHOSPHATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217963-A1 | SPHINOGOSINE-1-PHOSPHATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | S1PR1, SPHK1, S1PR3 | S1PR3 3/4885S1PR1 1/4885S1PR5 11/4885 |
| US-11034691-B2 | Sphinogosine-1 -phosphate receptor modulators for treatment of cardiopulmonary disorders | S1PR1, SPHK1, S1PR3 | S1PR3 3/4885S1PR1 1/4885S1PR5 11/4885 |
| US-20190300527-A1 | SPHINOGOSINE-1-PHOSPHATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | S1PR1, SPHK1, S1PR3 | S1PR3 3/4885S1PR1 1/4885S1PR5 11/4885 |
| US-10323029-B2 | Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders | S1PR1, SPHK1, S1PR3 | S1PR3 3/4885S1PR1 1/4885S1PR5 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.